Three Novel Cantharidin-Related Compounds from the Chinese Blister Beetle, Mylabris phalerata PALL.
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چکیده
منابع مشابه
Identification and Biochemical Characterization of Protein Phosphatase 5 from the Cantharidin-Producing Blister Beetle, Epicauta chinensis
Protein phosphatase 5 (PP5) is a unique member of serine/threonine phosphatases which has been recognized in regulation of diverse cellular processes. A cDNA fragment encoding PP5 (EcPP5) was cloned and characterized from the cantharidin-producing blister beetle, E. chinensis. EcPP5 contains an open reading frame of 1500 bp that encodes a protein of 56.89 kDa. The deduced amino acid sequence sh...
متن کاملEgg white, a favourable solvent to extract the active ingredient of Mylabris phalerata.
To characterize the role of hen eggs used for analyzing the insect Mylabris phalerata a traditional Chinese medicine for curing liver cancer, egg white was separated from the whole egg and added to M. phalerata. The volatile compounds found in egg white when added to M. phalerata and therefore in M. phalerata itself were analyzed by GC. Cantharidin was detected both in egg white added to M. pha...
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The dried body of Mylabris cichorii is well-known Chinese traditional medicine. The sesquiterpenoid cantharidin, which is secreted mostly by adult male beetles, has recently been used as an anti-cancer drug. However, little is known about the mechanisms of cantharidin biosynthesis. Furthermore, there is currently no genomic or transcriptomic information for M. cichorii. In this study, we perfor...
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Norcantharidin is the demethylated analog of cantharidin isolated from blister beetles (Mylabris phalerata Pall.). In this study, we evaluated whether norcantharidin exhibits anticancer effects against the human non-small cell lung cancer cell lines A549 (epidermal growth factor receptor (EGFR) mutation-negative) and PC9 (EGFR mutation-positive). ...
متن کاملEffect of Coumarin and Related Compounds on Blister Beetle Feeding in Sweetclover
The ashgray blister beetle. EpiCtluta [abricii (LeConte); th e striped blister beetle. E. lilt/ala (F.) ; and the margined bli ster beetle, E. p estijer« Werner. collected in the field from plants of sweetclover low in coumarin content, fed preferentially in the Iaboratory on low-coumarin leaves when offered a choice between leaves from highand low-coumarin plants. The black bli ster beetle. E....
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2004
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.52.807